Specification of the Nerve Cell Subtypes in the Developing Central Nervous System

Grant number: DP130102395 | Funding period: 2013 - 2017

Completed

Abstract

Different subtypes of nerve cells in the brain, which carry out distinct functions, are generated in the embryo by the co-ordinated action of many genes. This project aims to use the genetic advantages of the zebrafish to determine the role of genes in specifying the final fates of nerve cells in the retina, which analyses visual signals within the eye.

Related publications (3)

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S Dudczig, PD Currie, PR Jusuf

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Calcium binding proteins show stereotypical expression patterns within diverse neuron types across the central nervous system. Her..

In vivo expression of Nurr1/Nr4a2a in developing retinal amacrine subtypes in zebrafish Tg(nr4a2a:eGFP) transgenics

L Goodings, J He, AJ Wood, WA Harris, PD Currie, PR Jusuf

2017-06-01

The Nuclear receptor subfamily 4 group A member 2 (Nr4a2) is crucial for the formation or maintenance of dopaminergic neurons in t..

Biasing amacrine subtypes in the Atoh7 lineage through expression of barhl2

PR Jusuf, S Albadri, A Paolini, PD Currie, F Argenton, SI Higashijima, WA Harris, L Poggi

2012-10-03

Within the developing vertebrate retina, particular subtypes of amacrine cells (ACs) tend to arise from progenitors expressing the..

University of Melbourne Researchers

Patricia Jusuf